BUFFALO, N.Y. (AP) — In the first major league game in Buffalo since 1915, Travis Shaw hit an RBI single in the 10th inning and the Toronto Blue Jays settled into their new nest with a 5-4 win over the Miami Marlins on Tuesday night.

Barred from playing in Toronto by the Canadian government over concerns about the coronavirus, the Blue Jays spent nearly three weeks on the road before moving into the ballpark of their Triple-A affiliate as their temporary home this year.

Francisco Cervelli’s three-run homer with two outs in the Miami ninth made it 4-all. Logan Forsythe then nearly put the Marlins ahead with a long drive in the 10th that originally was ruled a two-run homer, then reversed to a foul ball on review — the replay cameras were among the upgrades made at the park to get it up to big-league standards.

The Blue Jays loaded the bases with one out in the 10th and Shaw singled to right field for his first RBI in 25 at-bats with Toronto.

Bo Bichette hit a three-run homer in the sixth and Cavan Biggio added an RBI single in the seventh for Toronto.

A.J. Cole (1-0) got the win. Stephen Tarpley (2-1) gave up Shaw’s game-ending hit.

Toronto starter Hyun Jin Ryu allowed two hits in six innings and struck out seven.

Brian Anderson also homered for Miami. Starter Elieser Hernandez struck out five over 5 1/3 innings.

ANGELS 6, ATHLETICS 0

ANAHEIM, Calif. (AP) — Dylan Bundy threw seven scoreless innings of four-hit ball, Jason Castro hit a three-run homer and Los Angeles defeated Oakland and won back-to-back games for the first time this season.

Anthony Rendon, Castro and Brian Goodwin homered in the fourth off Mike Fiers (1-1), and David Fletcher homered in the sixth inning to give the Angels back-to-back home games with at least four homers for the first time in franchise history.

That was more than enough offense for Bundy (3-1), who struck out 10 with one walk.

Fiers yielded seven hits and five runs while failing to get out of the fourth inning.

Ramón Laureano went 1 for 3 with two strikeouts for the A’s after appealing his six-game suspension handed down Tuesday for his role in Oakland’s fight with the Astros last weekend.

PADRES 6, DODGERS 2

LOS ANGELES (AP) — Manny Machado slugged a grand slam after two consecutive errors by the Dodgers in the third inning, Garrett Richards won for the first time in two years, and San Diego defeated Los Angeles.

The Padres have taken the first two games of the series after dropping two of three to the Dodgers last week in San Diego, and have won a season-best three in a row overall.

Richards (1-1) won his first game since July 4, 2018. The right-hander allowed one run and six hits in six innings. He struck out three and walked two.

Machado’s 10th career slam came off Ross Stripling (3-1).

Jurickson Profar hit a solo shot leading off the fifth. The Padres’ 32 homers lead the majors.

Stripling gave up six runs and six hits in 4 2/3 innings of his first loss of the season. He struck out four and walked two.

GIANTS 7, ASTROS 6, 10 innings

HOUSTON (AP) — Brandon Crawford’s RBI single in the 10th inning lifted the Giants to a win over the Astros.

Austin Slater singled off Cy Sneed (0-3) to start the 10th and send Wilmer Flores to third after he started on second under the new extra-innings rules. Crawford then followed with his grounder to center field to score Flores.

Trevor Gott (1-0) walked one in a scoreless ninth for the win and Tyler Rogers struck out two in a perfect 10th for his first save.

An RBI single by Darin Ruf off Ryan Pressly with one out in the ninth tied it at 6-all.

WHITE SOX 8, TIGERS 4

DETROIT (AP) — Eloy Jimenez hit a three-run homer in the first inning, and Chicago snapped Detroit’s four-game wining streak.

Edwin Encarnacion also went deep for the White Sox, who won for only the second time in seven games. Austin Romine hit a two-run shot for Detroit.

Jose Abreu had three hits, including a pair of RBI doubles.

Gio Gonzalez was pulled one out shy of the win. He allowed two runs and six hits in 4 2/3 innings. Matt Foster (2-0) was credited with the win after striking out four in two perfect innings.

Tyler Alexander (1-1) allowed five runs in 3 2/3 innings in his first start of the season.

Harold Castro hit an RBI single as part of Detroit’s two-run ninth.

CUBS 7, INDIANS 1

CLEVELAND (AP) — Jon Lester looked comfortable on a mound where he helped make history and Jason Heyward hit a three-run homer, leading Chicago to a win over Cleveland, which welcomed back manager Terry Francona after a couple of bumpy days.

Lester (2-0) allowed three hits in six innings as the Cubs moved to 11-3 for the first time since 2016.

For the first time this year, the Indians gave up more than four runs, ending the second-longest run (18 games) to open a season.

Francona returned after missing eight games to rest and treat a gastrointestinal ailment that has bothered him for nearly a year.

NATIONALS 2, METS 1

NEW YORK (AP) — Max Scherzer showed no effects of hamstring trouble, navigating heavy traffic early for his first win this season, and Trea Turner hit a record-breaking leadoff homer to help Washington beat New York.

Howie Kendrick had three hits and Victor Robles blooped an RBI single for the Nationals, who have taken the first two in a four-game series between NL East rivals. New York (7-11) dropped to 3-7 at home this season.

Rick Porcello (1-2) threw six solid innings but was outpitched by Scherzer (1-1).

Scherzer needed 60 pitches to get through the initial two innings but stranded five runners by striking out Wilson Ramos to end the first and Jeff McNeil to close the second.

He lasted six innings and threw only 45 pitches over his final four to finish with 105. He gave up six hits, struck out seven and walked two.

Turner hit his 10th career leadoff homer, a Nationals record. Alfonso Soriano hit nine in his lone season with Washington (2006).

YANKEES 9, BRAVES 6

NEW YORK (AP) — Aaron Judge dented an advertisement with a scorching home run before making an unusually early exit, Jordan Montgomery pitched efficiently against a lineup missing its brightest young star and New York beat Atlanta.

Atlanta scratched Ronald Acuña Jr. about 90 minutes before the first pitch with a sore left wrist.

Judge smashed his homer off a sign above the home bullpen in right-center field, leaving his mark on a shot leading off the fifth. Then his night came to a bizarre end. Yankees manager Aaron Boone sent Mike Tauchman to pinch-hit for Judge in the sixth inning with New York leading 8-3.

Luke Voit hit a three-run drive in the first inning off Braves starter Touki Toussaint (0-1), who allowed six runs — five earned — in four innings.

Montgomery (2-1) cruised through five innings before allowing a three-run homer to Marcell Ozuna in the sixth. He threw 78 pitches over six innings, allowing three runs, four hits and a walk with four strikeouts. Zack Britton pitched a perfect ninth inning for his sixth save.

REDS 6, ROYALS 5, 10 innings

CINCINNATI (AP) — Joey Votto doubled home the winning run in the 10th and Cincinnati blew another late lead before rallying past Kansas City.

The Royals tied it 5-5 in the eighth on Ryan McBroom’s pinch-hit, two-run homer off Amir Garrett, but they couldn’t keep their four-game winning streak going.

With a designated runner on second base in the 10th, Josh Staumont (0-1) walked Nick Castellanos and Votto doubled off the wall in center.

Lucas Sims (1-0) gave up a walk in the 10th with a designated runner on second base but escaped the threat.

Matt Davidson and Jesse Winker hit consecutive homers off left-hander Kris Bubic in his first road start as Cincinnati pulled ahead 5-3, but Cincinnati’s leaky bullpen let another lead slip away.

ORIOLES 10, PHILLIES 9, 10 innings

PHILADELPHIA (AP) — Austin Hays hit a two-run, inside-the-park homer in the 10th inning to lift Baltimore over Philadelphia.

Bryce Harper hit a tying, two-run homer in the eighth and Jean Segura gave the Phillies a 6-5 lead with a solo shot two outs later. But closer Hector Neris couldn’t hold it.

After Orioles closer Cole Sulser (1-1) allowed a two-run single to Didi Gregorius with two outs in the ninth to tie it at 8, Hays put Baltimore ahead to stay.

With a runner on second to start the extra-inning, Hays ripped a sinking liner to center off Deolis Guerra (1-2). Roman Quinn dove headfirst and the ball skipped to the warning track. Quinn fell picking it up and Hays circled the bases.

Paul Fry allowed an RBI single in the 10th but got a bouncer for the second out. Travis Lakins Sr. got Rhys Hoskins on a grounder, earning his first career save.

Phillies starter Zack Wheeler cruised into the sixth before running into trouble. He allowed three runs and eight hits in 5 2/3 innings.

Orioles starter Alex Cobb yielded three runs — two earned — and three hits in 5 1/3 innings.

RAYS 8, RED SOX 2

BOSTON (AP) — Mike Brosseau led off the game with a home run, Yandy Díaz and Hunter Renfroe each had two RBIs and Tampa Bay beat Boston.

Brosseau, Díaz and Manuel Margot had multi-hit games as Tampa Bay won its fourth straight game.

Tampa Bay starter Andrew Kittredge exited with right elbow soreness after throwing only five pitches. John Curtiss (1-0) pitched 2 2/3 innings of one-run ball in relief of Kittredge.

Michael Chavis and Alex Verdugo each hit RBI singles for the Red Sox. Martín Pérez (2-2) allowed two runs on three hits and struck out five in 5 2/3 innings after tossing five scoreless innings in a 5-0 win at Tampa Bay last Wednesday.

Boston has lost seven of its last 10.

BREWERS 6, TWINS 4

MILWAUKEE (AP) — Jedd Gyorko blasted a tiebreaking two-run homer in the eighth inning as Milwaukee came from behind to beat Minnesota.

The Brewers started their winning rally when Christian Yelich beat the Twins’ shift with a one-out double.

Gyorko followed with a shot to center off Taylor Rogers (1-2).

Eddie Rosario of the Twins and Manny Pina of the Brewers each hit two home runs. Minnesota’s Jorge Polanco and Milwaukee’s Avisail Garcia also homered.

RANGERS 4, MARINERS 2

ARLINGTON, Texas (AP) — Nick Solak singled three times and drove in three runs, leading Texas to a victory over Seattle.

Solak had a two-run single in the first and an RBI hit in third when Willie Calhoun added another run-scoring single. Calhoun’s hit scored slugger Joey Gallo, who was hit by a pitch twice and walked his other two times up.

Left-hander Mike Minor allowed an infield single and three walks with four strikeouts in four scoreless innings but was pulled after 76 pitches.

Edinson Volquez (2-1) was awarded the win by the official scorer after replacing Nick Goody, who came on after Minor and allowed both Seattle runs, one of them unearned. Rafael Montero pitched a perfect ninth for his third save.

Seattle starter Marco Gonzales (2-2) gave up seven hits and four runs in five innings.

ROCKIES 8, DIAMONDBACKS 7

DENVER (AP) — Charlie Blackmon raised his batting average to .500 with three hits, including a key double during a six-run burst in the eighth inning that led Colorado over Arizona.

After starting out the year 0 for 9, Blackmon has hit in 15 straight games. He’s 34 for 68 through 17 games in the coronavirus-shortened 60-game season.

Blackmon doubled off Kevin Ginkel (0-1) during the Rockies’ big inning that made it 8-2.

The Diamondbacks rallied for five runs in the ninth and had runners on first and third with two outs. Daniel Bard fanned pinch hitter Stephen Vogt to end it and earn his first save since 2011 while with the Boston Red Sox. It was his sixth career save overall.

Nolan Arenado hit a two-run homer and Raimel Tapia added three hits, including a two-run double in the eighth for Colorado.

Carlos Estevez (1-0) worked a scoreless eighth for the victory.

Christian Walker and Carson Kelly each homered for the Diamondbacks.